SYSTEM AND METHOD OF PREDICTING PERSONAL THERAPEUTIC RESPONSE
摘要
A system and method of predicting the course of progression of a disease and determining a personalized therapeutic regime for treating the disease in a subject includes obtaining the subject's normal-tissue transcriptome. The normal-tissue transcriptome is statistically correlated with the subject's perturbed transcriptome to identify one or more deregulated mechanisms; and statistics derived from the identified deregulated mechanism are used to predict the course of progression of the disease and to a recommend a personalized therapeutic regime for treating the disease. The perturbed transcriptome may in some cases be determined from a cancer of the subject, and in other cases from viral infected tissue cultured from the subject.
申请公布号
WO2015051192(A1)
申请公布日期
2015.04.09
申请号
WO2014US58924
申请日期
2014.10.02
申请人
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS;LUSSIER, YVES ANDRÉ;GARDEUX, VINCENT;ACHOUR, IKBEL