发明名称 |
FLUORESCENT PROBE FOR HIGH-SENSITIVITY PANCREATIC FLUID DETECTION, AND METHOD FOR DETECTING PANCREATIC FLUID |
摘要 |
[Problem] To provide a fluorescent probe capable of rapidly detecting and imaging with high sensitivity the presence of leakage of pancreatic fluid during or after surgery, and to furthermore provide a detection method and detection kit that use the fluorescent probe. [Solution] A fluorescent probe for detecting pancreatic fluid containing a compound or salt thereof represented by formula (I) below.
(In the formula, A represents an amino acid residue or N-substituted amino acid residue, with A forming an amide bond with the adjacent NH in the formula; R 1 represents a hydrogen atom or 1 to 4 same or different substituent groups that bond with a benzene ring; R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R 8 and R 9 each independently represent a hydrogen atom or an alkyl group; and X represents a C 1 -C 3 alkylene group.) |
申请公布号 |
EP2857830(A1) |
申请公布日期 |
2015.04.08 |
申请号 |
EP20130797296 |
申请日期 |
2013.05.29 |
申请人 |
THE UNIVERSITY OF TOKYO |
发明人 |
URANO, YASUTERU;SAKABE, MASAYO;NAGANO, TETSUO;ISHIZAWA, TAKEAKI;YAMASHITA, SUGURU;KOKUDO, NORIHIRO;KAMIYA, MAKO |
分类号 |
C07D493/10;A61K31/35;A61P35/00 |
主分类号 |
C07D493/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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