发明名称 FLUORESCENT PROBE FOR HIGH-SENSITIVITY PANCREATIC FLUID DETECTION, AND METHOD FOR DETECTING PANCREATIC FLUID
摘要 [Problem] To provide a fluorescent probe capable of rapidly detecting and imaging with high sensitivity the presence of leakage of pancreatic fluid during or after surgery, and to furthermore provide a detection method and detection kit that use the fluorescent probe. [Solution] A fluorescent probe for detecting pancreatic fluid containing a compound or salt thereof represented by formula (I) below. (In the formula, A represents an amino acid residue or N-substituted amino acid residue, with A forming an amide bond with the adjacent NH in the formula; R 1 represents a hydrogen atom or 1 to 4 same or different substituent groups that bond with a benzene ring; R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R 8 and R 9 each independently represent a hydrogen atom or an alkyl group; and X represents a C 1 -C 3 alkylene group.)
申请公布号 EP2857830(A1) 申请公布日期 2015.04.08
申请号 EP20130797296 申请日期 2013.05.29
申请人 THE UNIVERSITY OF TOKYO 发明人 URANO, YASUTERU;SAKABE, MASAYO;NAGANO, TETSUO;ISHIZAWA, TAKEAKI;YAMASHITA, SUGURU;KOKUDO, NORIHIRO;KAMIYA, MAKO
分类号 C07D493/10;A61K31/35;A61P35/00 主分类号 C07D493/10
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