发明名称 |
Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials |
摘要 |
The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions. |
申请公布号 |
US8999692(B2) |
申请公布日期 |
2015.04.07 |
申请号 |
US201213543627 |
申请日期 |
2012.07.06 |
申请人 |
Danisco US Inc. |
发明人 |
Cascao-Pereira Luis G.;Kaper Thijs;Kelemen Bradley R.;Liu Amy D. |
分类号 |
C12N9/42 |
主分类号 |
C12N9/42 |
代理机构 |
Danisco US Inc. |
代理人 |
Danisco US Inc. |
主权项 |
1. A cellulase variant obtained from a parent cellulase, wherein said variant is a mature form having cellulase activity, comprises a sequence that is at least 95% identical to the amino acid sequence of SEQ ID NO:3, and comprises a substitution at position 203, wherein the positions are numbered by correspondence with the amino acid sequence of SEQ ID NO:3, and wherein the substitution causes the cellulase variant to have a more negative net charge in comparison to the parent cellulase. |
地址 |
Palo Alto CA US |