发明名称 Selective glycosidase inhibitors and uses thereof
摘要 <p>The application relates to an immoalditol compound for selectively inhibiting glycosidases, a prodrug thereof and a pharmaceutical composition comprising the compound or the prodrug The application also relates to the use of the immoalditol compound for treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-G1cNAc Such diseases and disorders include neurodegenerative diseases, tauopathy, cancers, and cardiac disorders</p>
申请公布号 AU2009299073(B2) 申请公布日期 2015.04.02
申请号 AU20090299073 申请日期 2009.09.16
申请人 SIMON FRASER UNIVERSITY 发明人 VOCADLO, DAVID JARO;MCEACHERN, ERNEST JOHN
分类号 C07D207/12;A61K31/40;C12Q1/40 主分类号 C07D207/12
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