SILK PROTEIN FRAGMENT COMPOSITIONS AND ARTICLES MANUFACTURED THEREFROM

摘要

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.

主权项

1. A film comprising:
pure silk fibroin-based protein fragments substantially devoid of sericin and comprising:
an average weight average molecular weight ranging from about 17 kDa to about 38 kDa; anda polydispersity of between about 1.5 and about 3.0,wherein the film has a water content ranging from about 2.0 wt. % to about 20.0 wt. %,wherein the film includes between 0 ppm and 500 ppm of inorganic residuals,wherein the film includes between 0 ppm and 500 ppm of organic residuals, andwherein the film is sufficiently flexible to conform to anatomical topographies.