发明名称 NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
申请公布号 SG11201500845U(A) 申请公布日期 2015.03.30
申请号 SG11201500845U 申请日期 2013.08.07
申请人 THERAVANCE BIOPHARMA R&D IP, LLC 发明人 FLEURY, MELISSA;HUGHES, ADAM D.
分类号 C07D231/14;A61K31/415;A61K31/4192;A61K31/42;A61K31/421;A61P9/12;C07D249/04;C07D261/18;C07D263/38;C07D405/12 主分类号 C07D231/14
代理机构 代理人
主权项
地址