摘要 |
PROBLEM TO BE SOLVED: To provide octreotide analogs excellent in tumor-accumulating capacity in which kidney accumulation is reduced over a long time.SOLUTION: The invention provides octreotide analogs represented by the sequence of the following formula (1), or a salt thereof. The formula (1) is DTPA-Phe-X-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr(ol) (in the formula (1), X is an acidic amino acid, Phe residues of N terminal may be any of the D form and the L form, Thr(ol) represents a L-threoninol residue, the two Cys residues are bond to each other by a disulfide bond). And a complex of the above octreotide analogs and radioactive indium, and a radioactive diagnostic imaging agent containing the complex as an active ingredient are also provided. |