摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to new chromone derivatives of general formula,wherein: R1 represents one or more identical or different substitutes on a benzene ring, each of which independently represents a hydrogen atom, or a halogen atom, or Calkoxy group, or OH group. or group -O(CH)O-, wherein n=1 or 2, R2 represents a hydrogen atom, or Calkyl group; A and B independently represent either a nitrogen atom, or a carbon atom; R3 represents a hydrogen atom or one or more identical or different substitutes specified in a group consisting of: a halogen atom, Calkyl group, Calkoxy group, group -O(CH)O-, wherein n=1 or 2, group NO, group NHSOR4, group NHR5, OH group, Chalogenoalkyl group, CN group, or R3 makes a ring condensed with a benzene ring bearing it, specified in a group consisting of indole, benzimidazole, carbostyril, benzoxazolone and benzoxazolone and benzimidazolone, R4 represents Calkyl group, or Cdialkylamino group, or Calkoxyalkyl group, or Cdialkylaminoalkyl group, R5 represents a hydrogen atom, or Calkylcarbonyl group, or Calkoxycarbonyl group, and to its pharmaceutically acceptable salts, as well as to methods for preparing them, and to based pharmaceutical compositions, and to using them as a therapeutic agent for central nervous system disorders, as long as they possess the D3 dopaminergic ligand properties.EFFECT: preparing the compositions for treating central nervous system disorders, as long as they possess the D3 dopaminergic ligand properties.17 cl, 1 dwg, 2 tbl, 33 ex |