Her2 binding peptides labelled with a 18f - containing organosilicon compound

摘要

Disclosed is an imaging agent composition that comprises an isolated polypeptide comprising SEQ. ID No. 1 or SEQ. ID. No 2, conjugated with 18F-SiFA via an isotopic fluorine exchange chemistry wherein the isolated polypeptide binds specifically to HER2 or variants thereof; wherein the sequences are as defined in the specification. Also disclosed are methods of making such an imagining agent.