发明名称 METHODS FOR TREATING HCV COMPRISING AT LEAST TWO DIRECT-ACTING ANTIVIRAL AGENTS, RIBAVIRIN, BUT NOT INTERFERON
摘要 PROBLEM TO BE SOLVED: To provide a therapeutic method for treating Hepatitis C Virus (HCV) not using interferon.SOLUTION: Provided is a method for treating HCV 1 infection comprising administering to a HCV patient at least two direct-acting antiviral agents (DAAs) and ribavirin, where the method does not comprise administration of interferon to the patient, the at least two DAAs include a HCV polymerase inhibitor and HCV NS5A inhibitor, and the treatment continues 8, 9, 10 or, 11 weeks. The at least 2 DAAs may include one of PSI-7977, TMC-435, daclatasvir, and GS-5885, or may be any combination of BM-790052 and BMS-650032, mericitabine, danoprevir or INX-189 and daclatasvir.
申请公布号 JP2015057395(A) 申请公布日期 2015.03.26
申请号 JP20140208294 申请日期 2014.10.09
申请人 ABBVIE INC 发明人 BARRY M BERNSTEIN;RAJEEV M MENON;AMIT KHATRI;SVEN MENSING;SANDEEP DUTTA;DANIEL E COHEN;THOMAS J PODSADECKI;SCOTT C BRUN;WALID M AWNI;EMILY O DUMAS;CHERI E KLEIN
分类号 A61K31/7056;A61K45/06;A61P1/16;A61P31/14;A61P43/00 主分类号 A61K31/7056
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