发明名称 |
METHODS AND COMPOSITIONS FOR IMAGING DISORDERS USING POLYSPECIFIC AGENTS |
摘要 |
The present invention provides compositions and methods for detecting and/or monitoring a disease state with polyspecific imaging agents. In a particular embodiment, provided methods may be used to assess efficacy of anti-receptor tyrosine kinase and/or anti-cancer treatments. In some embodiments, the present invention provides methods and compositions relating to polyspecific imaging agents that target neurological, tumor-associated and/or intratumoral markers. For example, the present invention provides compositions, including pharmaceutical compositions, comprising anti-receptor tyrosine kinase antibodies, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using anti-receptor tyrosine kinase antibodies and/or compositions. |
申请公布号 |
WO2015042275(A1) |
申请公布日期 |
2015.03.26 |
申请号 |
WO2014US56332 |
申请日期 |
2014.09.18 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
VILLEGAS, NERISSA, THERESE, V.;LEWIS, JASON, S. |
分类号 |
A61B5/055 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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地址 |
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