USE OF QUATERNARY PYRIDINIUM SALTS FOR INHIBITING CANCER METASTASES

摘要

The invention relates to a method for inhibiting and/or preventing formation of cancer metastases and secondary malignant cancers by administration to a subject of an effective amount of a quaternary pyridinium salt of formula (I) wherein R' is selected from the group consisting of H, OH, CONH2, and COCH3; R" is selected from the group consisting of H and CH3, R'" is selected from the group consisting of H and CH3; and X- is a pharmaceutically acceptable counterion.