发明名称 |
METHOD FOR PRODUCING AND OBTAINING VARIABLE DOMAINS OF ANTI-DIGOXIN MONOCLONAL ANTIBODY FAB FRAGMENT USING THE MOLECULAR BIOLOGY CLONING TECHNIQUE |
摘要 |
Method for producing and obtaining variable domains of anti-digoxin monoclonal antibody Fab fragment using the molecular biology cloning technique, and more precisely the present patent of invention relates to a method for producing and obtaining clones of the anti-digoxin antibody Fab fragment using phage display technology and the characterization of the binding thereof to the antigen; the present innovation pertains to the development of the product for therapeutic use having specific potency and a more precise dose for detoxification of patients undergoing treatment with digoxin. |
申请公布号 |
EP2851427(A1) |
申请公布日期 |
2015.03.25 |
申请号 |
EP20130804686 |
申请日期 |
2013.05.15 |
申请人 |
FUNDAÇÃO BUTANTAN |
发明人 |
KALIL FILHO, JORGE ELIAS;MORO, ANA MARIA;MIDORI MURATA, VIVIANE;RUMI TSURATA, LILIAN;COSTA BRAGA SCHMIDT, MARIANA |
分类号 |
C12N15/13;C07K16/16;C12N15/70;G01N33/53 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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