发明名称 METHOD FOR PRODUCING AND OBTAINING VARIABLE DOMAINS OF ANTI-DIGOXIN MONOCLONAL ANTIBODY FAB FRAGMENT USING THE MOLECULAR BIOLOGY CLONING TECHNIQUE
摘要 Method for producing and obtaining variable domains of anti-digoxin monoclonal antibody Fab fragment using the molecular biology cloning technique, and more precisely the present patent of invention relates to a method for producing and obtaining clones of the anti-digoxin antibody Fab fragment using phage display technology and the characterization of the binding thereof to the antigen; the present innovation pertains to the development of the product for therapeutic use having specific potency and a more precise dose for detoxification of patients undergoing treatment with digoxin.
申请公布号 EP2851427(A1) 申请公布日期 2015.03.25
申请号 EP20130804686 申请日期 2013.05.15
申请人 FUNDAÇÃO BUTANTAN 发明人 KALIL FILHO, JORGE ELIAS;MORO, ANA MARIA;MIDORI MURATA, VIVIANE;RUMI TSURATA, LILIAN;COSTA BRAGA SCHMIDT, MARIANA
分类号 C12N15/13;C07K16/16;C12N15/70;G01N33/53 主分类号 C12N15/13
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