LATEX PARTICLES FOR AGGLUTINATION ASSAY

摘要

A latex particle for high-sensitive agglutination assay and a reagent for agglutination assay including the particle are provided. The latex particle barely initiates non-specific reactions and can readily prepare diagnostic agents. A latex particle for agglutination assay including a polymerizable monomer having a phenyl group, a polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a polymerizable monomer represented by Formula (1):;CH2═CR1—COO(CH2CH2O)n—R2  (1);where R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a methyl group; and n is 1≦n<20, wherein the density of functional groups derived from the polymerizable monomer represented by Formula (1) on the surface of the particle is 0.05 to 0.5 μmol/m2.

主权项

1. A latex particle for agglutination assay, comprising:
a polymerizable monomer having a phenyl group, a polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a polymerizable monomer represented by Formula (1):
CH2═CR1—COO(CH2CH2O)n—R2  (1)where R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a methyl group; and n is 1≦n<20,
wherein the density of functional groups derived from the polymerizable monomer represented by Formula (1) on the surface of the particle is 0.05 to 0.5 μmol/m2.