发明名称 METHOD AND COMPOSITION FOR TREATING SEROTONIN RECEPTOR-MEDIATED CONDITION
摘要 PROBLEM TO BE SOLVED: To provide a method and composition for treating serotonin (5-HT) receptor-mediated conditions, including, but not limited to, platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attacks, stable angina, unstable angina, thrombotic stroke, a secondary ischemic event (e.g., reversible ischemic neurological deficit and intermittent claudication), atrial fibrillation, thrombosis (e.g., clot formation associated with angioplasty, cardiac surgery, and/or atrial fibrillation), restenosis (including, e.g., by treatment with a medicated device, such as a medicated stent), asthma, and pathologies associated with diabetes (e.g., diabetic nephropathy and diabetic retinopathy).SOLUTION: A pharmaceutical composition contains 4-[3-[4-(6-fluoro-1,2-benzisoxazole-3-yl)-1-piperidinyl] propoxy]-3-methoxybenzoic acid or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable additive thereof.
申请公布号 JP2015051991(A) 申请公布日期 2015.03.19
申请号 JP20140226131 申请日期 2014.11.06
申请人 VANDA PHARMACEUTICALS INC 发明人 POLYMEROPOULOS MIHAEL H;PAOLO BAROLDI;CURT D WOLFGANG
分类号 A61K31/454;A61K31/352;A61K31/4365;A61K31/616;A61K38/48;A61K45/00;A61P3/10;A61P7/02;A61P9/00;A61P11/06;A61P43/00 主分类号 A61K31/454
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