发明名称 |
Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels |
摘要 |
<p>Compositions for increasing red blood cell levels or treatment of anemia comprising erythropoietin receptor activators and a variant Activin RIIB (ActRIIB) polypeptide having a leucine residue replaced by a acidic amino acid residue, where the variant ActRIIB polypeptide has a reduced affinity for activin B and may be called a GDF trap. Methods for the use of these compositions.</p> |
申请公布号 |
AU2010282361(B2) |
申请公布日期 |
2015.03.19 |
申请号 |
AU20100282361 |
申请日期 |
2010.08.13 |
申请人 |
ACCELERON PHARMA INC. |
发明人 |
SEEHRA, JASBIR;PEARSALL, ROBERT SCOTT;KUMAR, RAVINDRA |
分类号 |
C07K19/00;A61K38/00;A61K38/18;A61P7/06 |
主分类号 |
C07K19/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|