Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer
摘要
The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
formula:
or a pharmaceutically acceptable salt thereof.
申请公布号
EP2444085(B1)
申请公布日期
2015.03.18
申请号
EP20110184401
申请日期
2006.03.29
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人
SAWYERS, CHARLES L.;JUNG, MICHAEL E.;CHEN, CHARLIE D.;OUK, SAMEDY;WELSBIE, DEREK;TRAN, CHRIS;WONGPIVAT, JOHN;YOO, DONGWON