| 主权项 |
1. A compound of the Formula I: wherein A is aryl or heteroaryl, optionally substituted with C1-C4 alkyl, halogen, OH, CN, or N(R4)2, Ri is absent, H, OH, halogen, N(R4)2, or C1-C4 alkyl optionally substituted with halogen, OH, O-alkyl, CN, or N(R4)2; R2 and R3 are independently selected from H, halogen or C1-C4 alkyl optionally substituted with halogen, OH, CN, or N(R4)2, or R2 and R3, taken together may form a 4-7 membered saturated or unsaturated ring, optionally incorporating 0-3 N, O, or S atoms; wherein the 4-7 membered ring is optionally substituted with C1-C4 alkyl, halogen, OH, carbonyl, CN, halogen, or N(R4)2, or R2 and R3, can be taken together to form a carbonyl; each R4 is independently H, alkyl, or aryl, or two R4 can be taken together to form a 4-7 membered ring, optionally incorporating 0-3 N, O, S atoms; wherein the 4-7 membered ring is optionally substituted with C1-C4 alkyl, halogen, OH, CN, halogen, or N(R4)2; R5 is independently H or alkyl, or both R5 can be taken together to form a carbonyl; R7 and Rg are independently H or alkyl optionally substituted with C1-C4 alkyl, halogen, OH, CN, or N(R4)2; n is 0 or 1; p is 1 or 2; and wherein the symbol indicates a single or double bond; or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, or tautomer thereof. |
