| 发明名称 |
USE OF RBM39 AS A BIOMARKER |
| 摘要 |
The present invention relates to the use (i) of a level of expression of a long RBM39 protein isoform, termed RBM39L, and (ii) of a level of expression of a short RBM39 protein isoform, termed RBM39C, as a marker for the efficacy of an active agent capable of preventing and/or treating HIV infection. |
| 申请公布号 |
US2015072892(A1) |
申请公布日期 |
2015.03.12 |
| 申请号 |
US201314383395 |
申请日期 |
2013.03.04 |
| 申请人 |
SPLICOS |
发明人 |
Tazi Jamal;Venables Julian;Garcel Aude;Campos Noëlle;Mahuteau-Betzer Florence;Najman Romain;Scherrer Didier |
| 分类号 |
C12Q1/68;G01N33/50 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for evaluating the efficacy of an active substance suitable for preventing and/or treating an HIV infection comprising determining (i) an expression level of a long isoform of an RBM39 protein, called RBM39L, and (ii) an expression level of a short isoform of an RBM39 protein, called RBM39S. |
| 地址 |
Montpellier FR |
