发明名称 CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS
摘要 The present invention relates to cyclic peptidomimetic compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signalling pathway. The invention also relates to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.
申请公布号 WO2015033303(A1) 申请公布日期 2015.03.12
申请号 WO2014IB64283 申请日期 2014.09.05
申请人 AURIGENE DISCOVERY TECHNOLOGIES LIMITED 发明人 SASIKUMAR, POTTAYIL GOVINDAN NAIR;RAMACHANDRA, MURALIDHARA;NAREMADDEPALLI, SEETHARAMAIAH SETTY SUDARSHAN
分类号 A61K31/38;A61K31/395;C07D273/00;C07D285/00 主分类号 A61K31/38
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