| 发明名称 |
POLYPEPTIDES AS APELIN INHIBITORS AND USES THEREOF |
| 摘要 |
The present invention relates to polypeptides and their uses as apelin inhibitors. More particularly, the present invention relates to a polypeptide comprising the sequence as set forth in SEQ ID NO:1 wherein at least one arginine residue at position 18, 19, 22 or 23 has been substituted or deleted. |
| 申请公布号 |
US2015072932(A1) |
申请公布日期 |
2015.03.12 |
| 申请号 |
US201314391404 |
申请日期 |
2013.04.09 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) ;UNIVERSITE PARIS-SUD XI ;UNIVERSITY DE BORDEAUX |
发明人 |
Siegfried Geraldine;Khatib Abdel-Majid |
| 分类号 |
C07K14/575 |
主分类号 |
C07K14/575 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polypeptide comprising the sequence as set forth in SEQ ID NO:1 or a function conservative variant thereof wherein at least one arginine residue at position 18, 19, 22 or 23 has been substituted or deleted. |
| 地址 |
Paris FR |
