Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.
申请公布号
EP2323947(A4)
申请公布日期
2015.03.11
申请号
EP20090840552
申请日期
2009.08.06
申请人
LIFE TECHNOLOGIES CORPORATION
发明人
TULSKY, ERIC;HALEY, KARI;NAASANI, IMAD;MAURO, JOHN, MATTHEW;ROZHKOV, ROMAN;TREADWAY, JOESEPH, A.