发明名称 |
CYCLOSPORINE-CONTAINING, NON-IRRITATIVE NANOEMULSION OPTHALMIC COMPOSITION |
摘要 |
Provided is an ophthalmic composition containing cyclosporine as an active ingredient and including polyethoxylated castor oil or polyethoxylated hydrogenated castor oil, and a method of preparing the same. Particularly, the ophthalmic composition is prepared as a nanoemulsion having a particle diameter of 100 nm or less simply by mixing and stirring an oil phase and an aqueous phase without using a high speed stirring or shearing machine, so that it is very physiochemically stable and storable for a long time. In addition, the ophthalmic composition causes no irritation to eyes. |
申请公布号 |
EP2845602(A1) |
申请公布日期 |
2015.03.11 |
申请号 |
EP20130784924 |
申请日期 |
2013.01.22 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY;HUONS CO., LTD. |
发明人 |
HWANG, SUNG JOO;CHA, KWANG HO;KANG, HAN;SUN, BO KYUNG |
分类号 |
A61K38/13;A61K9/10;A61K47/44;A61P27/02 |
主分类号 |
A61K38/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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