| 发明名称 | Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same | ||
| 摘要 | The present invention proposes a magnetic nanocomposite with multi-biofunctional groups, which comprises a core and a shell wrapping the core, wherein the core contains magnetic nanoparticles, and wherein the shell is made of a conductive polymer with multi-biofunctional groups where a medicine, an antibody or a fluorescent label can be attached. | ||
| 申请公布号 | US8974769(B2) | 申请公布日期 | 2015.03.10 |
| 申请号 | US201012799893 | 申请日期 | 2010.05.04 |
| 申请人 | Chang Gung University | 发明人 | Hua Mu-Yi;Yang Hung-Wei;Tsai Rung-Ywan;Wei Kuo-Chen;Chen Pin-Yuan;Liu Hao-Li |
| 分类号 | A61K49/18;A61K47/34;A61K9/50;A61K31/785;A61K47/48;B82Y5/00 | 主分类号 | A61K49/18 |
| 代理机构 | Muncy, Geissler, Olds & Lowe, P.C. | 代理人 | Muncy, Geissler, Olds & Lowe, P.C. |
| 主权项 | 1. A magnetic nanocomposite with multi-biofunctional groups, comprising a core formed of magnetic nanoparticles; and a shell wrapping said core and made of a polyaniline derivative conductive polymer with multi-biofunctional groups, wherein said polyaniline derivative conductive polymer has a structure expressed by Formula (I): wherein 0<x<1; wherein each of R1, R2, R3, R4 is selected from a group consisting of —H, —CH3, —C2H5, —C3H7, —F, —Cl, —Br, —I, —COR7, —OCOR7, —COOR7, and —CN; R7 is a C1-C8 alkyl functional group; and each of R5 and R6 is said multi-biofunctional group expressed as the following structure wherein R′═CH2CH2 or CH═CH, and wherein M=H, Li, Na, K, or NH4+. | ||
| 地址 | Kwei-Shan, Tao-Yuan TW | ||