Multimeric oxidoreductases

摘要

Described herein are multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate. The complexes comprise a dehydrogenase subunit and a cytochrome C subunit. Also described are polynucleotides coding for the multimeric complexes and methods of use thereof.

主权项

1. A method for producing a desired product comprising,
contacting an altered bacterial host cell with a polyol substrate under suitable culture conditions, wherein the altered bacterial host cell is obtained by the transformation of a bacterial host cell with a polynucleotide coding for a multimeric oxidoreductase complex selected from SEQ ID NO: 5 and SEQ ID NO: 23 and wherein the polynucleotide encoding the multimeric oxidoreductase complex is expressed in the altered bacterial host cell and producing a desired product from an enzymatic conversion of the polyol substrate by the multimeric oxidoreductase complex to said desired product.