发明名称 |
Mitochondrial activity inhibitors of cancer-initiating cells and use thereof |
摘要 |
The present invention relates to the compounds useful in the prevention and/or treatment of tumours. More specifically the present invention relates to inhibitors of the activity of the electron transport chains and/or the mitochondrial TCA cycle in glioma-initiating cells (GICs) for use in a method for preventing and/or treating tumours presenting glioma-initiating cells (GICs) in a subject who has undergone a prior removal of a tumour glioma bulk. The present invention further provides a pharmaceutical composition containing the inhibitors of the invention and a screening method for identifying the inhibitors of the invention. |
申请公布号 |
AU2010250814(B2) |
申请公布日期 |
2015.03.05 |
申请号 |
AU20100250814 |
申请日期 |
2010.05.20 |
申请人 |
HOPITAUX UNIVERSITAIRES DE GENEVE;UNIVERSITE DE GENEVE |
发明人 |
CLEMENT, VIRGINIE;RADOVANOVIC, IVAN |
分类号 |
A61K31/03;A61K31/343;A61K31/352;A61K31/357;A61K31/55;A61P35/00;G01N33/569;G01N33/574 |
主分类号 |
A61K31/03 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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