发明名称 2,2-DIFLUORODIOXOLO A2A RECEPTOR ANTAGONISTS
摘要 The present invention is directed to 2,2-difluorodioxolo compounds that are antagonists of A2A receptor. The present invention is also directed to uses of the 2,2- difluorodioxolo compounds described herein in the potential treatment or prevention of 5 neurological disorders and diseases in which A2A receptor are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds and to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which A2A receptors are involved.
申请公布号 WO2015031221(A1) 申请公布日期 2015.03.05
申请号 WO2014US52442 申请日期 2014.08.25
申请人 MERCK SHARP & DOHME CORP.;ALI, AMJAD;GALLO, GIOCONDA, V.;HENDERSON, TIMOTHY, J.;KUANG, RONGZE;LIM, YEON-HEE;LO, MICHAEL MAN-CHU;METZGER, EDWARD;RUIZ, MANUEL DE LERA;STAMFORD, ANDREW;TEMPEST, PAUL;WHITEHEAD, BRENT;WU, HEPING 发明人 ALI, AMJAD;GALLO, GIOCONDA, V.;HENDERSON, TIMOTHY, J.;KUANG, RONGZE;LIM, YEON-HEE;LO, MICHAEL MAN-CHU;METZGER, EDWARD;RUIZ, MANUEL DE LERA;STAMFORD, ANDREW;TEMPEST, PAUL;WHITEHEAD, BRENT;WU, HEPING
分类号 A01N43/58;A01N43/60 主分类号 A01N43/58
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