Aqueous ophthalmic solution based on cyclosporin

摘要

Described herein is an aqueous ophthalmic solution containing an immunosuppressive agent, such as cyclosporin A, and at least three polymers. The three polymers are preferably a combination of a cellulose derivative, a polyvinyl derivative, and a macrogolglycerol hydroxystearate.

主权项

1. An aqueous ophthalmic solution comprising an immunosuppressive agent, a first polymer, a second polymer, and a third polymer, wherein:
the immunosuppressive agent is cyclosporin A, wherein cyclosporin A is equal to or greater than 0.05% by weight of the solution; the first polymer is a cellulose derivative; the second polymer is a polyvinyl derivative; and the third polymer is a polymer with a lipophilic functional group.