Analyte sensors and methods

摘要

Methods of determining analyte concentration. The methods use a fraction of the predicted total charge, from analyte electrolysis, instead of using time, for determination of a data collection endpoint. The total charge is then extrapolated from the data collection endpoint. The analyte concentration is determined from the total charge.

主权项

1. A method for determining the concentration of an analyte in a sample, the method comprising:
receiving a sample to an analyte sensor, wherein the analyte sensor comprises a working electrode and a counter electrode; electrolysing the sample; measuring current as a function of time; predicting a first total signal value for complete electrolysis of the analyte from the measured current decay prior to a first time during electrolysis and an extrapolated current decay subsequent the first time during electrolysis; determining a data collection endpoint, wherein the data collection endpoint is a predetermined percentage of the predicted first signal value; measuring current until the data collection endpoint; calculating a second total signal value from the measured current decay prior to the data collection endpoint and an extrapolated current decay subsequent the data collection point; and determining the concentration of the analyte based on the calculated second signal value.