发明名称 Methods for treating chronic pelvic pain syndrome
摘要 The present invention provides methods and compositions for treating chronic pelvic pain syndrome. In particular, the present invention provides methods and compositions for treating chronic pelvic pain syndrome with an agent that targets MCP-1, MIP-1α, or the CCR-2 receptor.
申请公布号 US8969340(B2) 申请公布日期 2015.03.03
申请号 US201313936860 申请日期 2013.07.08
申请人 Northwestern University 发明人 Schaeffer Anthony J.;Klumpp David;Thumbikat Praveen
分类号 A61K31/537;A61K31/454;A61K31/495;G01N33/53;C12Q1/68;G01N33/68;A61K31/351;A61K31/40 主分类号 A61K31/537
代理机构 Casimir Jones S.C. 代理人 Casimir Jones S.C.
主权项 1. A method of treating a male subject having, or suspected of having, chronic pelvic pain syndrome comprising: treating a subject with an agent that targets MCP-1, MIP-1α, or the CCR-2 receptor, wherein said subject has one or more symptoms of chronic pelvic pain syndrome, wherein said agent is selected from the group consisting of: an indolopiperidine, a spiropiperidine, a 2-substituted indole, a pyrazolone derivative, a 2-substituted benzimidazole, an N,N-dialkylhomopiperazine, a bicyclic pyrrole, a 5-aryl pentadienamide, and a cyclic amine derivative; and wherein said treating is under conditions such that at least one of said symptoms is reduced or eliminated.
地址 Evanston IL US