发明名称 MATERIAL, METHOD FOR PREPARING SAME, AND USES THEREOF
摘要 A material including a continuous aqueous phase and a dispersed phase in the form of droplets containing an amphiphilic lipid and a surfactant having the following formula (I):;(L1-X1—H1—Y1)v-G-(Y2—H2—X2-L2)w   (I),;wherein: L1 and L2 independently represent lipophilic groups,X1, X2, Y1, Y2 and G independently represent a linking group,H1 and H2 independently represent hydrophilic groups including a polyalkoxylated chain,v and w are independently an integer from 1 to 8, wherein the droplets of the dispersed phase are covalently bonded by the surfactant having the formula (I). The invention also relating to the method for preparing the same and to the uses thereof.
申请公布号 US2015057374(A1) 申请公布日期 2015.02.26
申请号 US201314389432 申请日期 2013.04.02
申请人 COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES 发明人 Couffin Anne-Claude;Delmas Thomas;Heinrich Emilie;Texier-Nogues Isabelle;Thomann Jean-Sébastien;Mourier Véronique
分类号 A61K47/24;A61K47/20 主分类号 A61K47/24
代理机构 代理人
主权项 1. A method for preparing a material comprising of a continuous aqueous phase and a dispersed phase, dispersed in the form of droplets containing a phospholipid and a surfactant having the following formula (I): (L1-X1—H1—Y1)v-G-(Y2—H2—X2-L2)w   (I),wherein: L1 and L2 independently represent lipophilic groups, X1, X2, Y1, Y2 and G independently represent a linking group, H1 and H2 independently represent hydrophilic groups including a polyalkoxylated chain, v and w are independently an integer from 1 to 8,the said method comprising bringing into contact: an emulsion 1 comprising a continuous aqueous phase and a dispersed phase, dispersed in the form of droplets containing an phospholipid and a surfactant having the following formula (LI): L1-X1—H1—Y1-G1   (LI),with an emulsion 2 comprising a continuous aqueous phase and a dispersed phase, dispersed in the form of droplets containing an phospholipid and a surfactant having the following formula (LII): G2-Y2—H2—X2-L2   (LII)where G1 and G2 are groups that are capable of reacting in order to form the G group, under conditions that allow for the reaction of the surfactants having the formulas (LI) and (LII) in order to form the surfactant having the formula (I), whereby covalent bonds between the droplets of the dispersed phase are formed.
地址 Paris FR