发明名称 |
PREPARATION CONTAINING HIGHLY PURIFIED BOTULINUM TOXIN TYPE A DERIVED FROM INFANT BOTULISM PATHOGEN |
摘要 |
A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity. |
申请公布号 |
EP2085093(B1) |
申请公布日期 |
2015.02.25 |
申请号 |
EP20070830661 |
申请日期 |
2007.10.26 |
申请人 |
THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE;THE UNIVERSITY OF TOKUSHIMA |
发明人 |
HARAKAWA, TETSUHIRO;NAKANO, HIROTOSHI;TORII, YASUSHI;GOTO, YOSHITAKA;SHINMURA, MIHO;OKUDA, SACHIO;KAJI, RYUJI;KOSAKI, SHUNJI |
分类号 |
A61K38/48;A61K47/42;A61P1/00;A61P7/12;A61P17/00;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/16;A61P27/02;A61P43/00 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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