发明名称 Methods and compositions for treating HIV-associated diarrhea
摘要 Presented herein are methods for treating diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.
申请公布号 US8962680(B2) 申请公布日期 2015.02.24
申请号 US201113285397 申请日期 2011.10.31
申请人 Salix Pharmaceuticals, Ltd.;Napo Pharmaceuticals, Inc. 发明人 Forbes William;Bortey Enoch;King Steven;Chaturvedi Pravin
分类号 A61K31/352;A61P1/12;A61P1/00;A61K31/353;A61K31/05 主分类号 A61K31/352
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP ;Sparks Jonathan M.;Clarke Marcie B.
主权项 1. A method of treating stool consistency in an HIV positive subject, comprising: administering about 250 mg of crofelemer per day to the HIV positive subject.
地址 Raleigh NC US