发明名称 MODIFIED POLYNUCLEOTIDES FOR THE TREATMENT OF OTIC DISEASES AND CONDITIONS
摘要 The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides in the treatment, prevention and/or amelioration of otic diseases or conditions.
申请公布号 US2015050354(A1) 申请公布日期 2015.02.19
申请号 US201414508631 申请日期 2014.10.07
申请人 MODERNA THERAPEUTICS, INC. 发明人 Bouchon Axel;Chakraborty Tirtha
分类号 A61K48/00;A61K9/16 主分类号 A61K48/00
代理机构 代理人
主权项 1. A method of treating an otic disease, disorder or condition comprising administering to a subject a pharmaceutical composition comprising a polynucleotide encoding at least one otic polypeptide and wherein said polynucleotide is formulated in a pharmaceutically acceptable carrier or excipient.
地址 Cambridge MA US