| 发明名称 |
Derivados de indol como antagonistas del receptor CRTH2 en combinación con un segundo ingrediente activo |
| 摘要 |
<p>Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma in combination with a second active ingredient such as a leukotriene antagonist.</p> |
| 申请公布号 |
ES2529420(T3) |
申请公布日期 |
2015.02.19 |
| 申请号 |
ES20120168410T |
申请日期 |
2010.02.19 |
| 申请人 |
MERCK SHARP & DOHME CORP.;MERCK CANADA INC. |
发明人 |
BERTHELETTE, CARL;BOYD, MICHAEL;COLUCCI, JOHN;VILLENEUVE, KARINE;METHOT, JOEY |
| 分类号 |
C07D403/04;A61K31/405;A61K31/4192;A61K31/435;A61P11/06;C07D471/04 |
主分类号 |
C07D403/04 |
| 代理机构 |
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