SUSTAINED-RELEASE DRUG CARRIER COMPOSITION

摘要

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

主权项

1. A matrix composition comprising:
a. a biodegradable polymer in association with a first lipid having a polar group; b. a second lipid comprising at least one phospholipid having hydrocarbon chains of at least 14 carbons; c. a pharmaceutical active agent;
where the matrix composition is adapted for providing sustained release of the pharmaceutical active agent.