| 发明名称 |
New stable salt of 5,10-methylene-(6R)-tetrahydrofolic acid |
| 摘要 |
The present invention is directed towards the hemisulfate salt of 5,10-methylene-(6R)-tetrahydrofolic acid, preferably in substantially crystalline form, as well as pharmaceutical compositions and uses thereof in therapy, preferably chemotherapy. |
| 申请公布号 |
EP2837631(A1) |
申请公布日期 |
2015.02.18 |
| 申请号 |
EP20130004050 |
申请日期 |
2013.08.14 |
| 申请人 |
MERCK & CIE |
发明人 |
MOSER, RODOLF;GROEHN, VIOLA;EGGER, THOMAS;AMMANN, THOMAS |
| 分类号 |
C07D475/04;A61K31/519;A61P35/00 |
主分类号 |
C07D475/04 |
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