杂环衍生物;HETEROCYCLIC DERIVATIVES

摘要

本发明提供式(I)化合物，;包含该等化合物之组合物；该等化合物在疗法中(例如在治疗或预防其中牵涉血浆激肽释放素活性之疾病或病状中)的用途；及用该等化合物治疗患者之方法；其中R5、R6、R7、A、B、W、X、Y及Z如本文所定义。; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.