发明名称 ANTIBODIES, COMPOUNDS AND DERIVATIVES THEREOF FOR USE IN THE TREATMENT OF MALE INFERTILITY
摘要 The present invention relates to antagonists or inhibitors, which bind selectively to RANKL/OPGbp and regulate the interaction between RANKL/OPGbp and RANK/OPG.In particular, the present invention relates to an antibody or antigen binding domain, fragment or derivative thereof,immunoreactive with a RANKL/OPGbppeptidefor use in the treatment, prevention or alleviation of male infertility or reduced male fertility such as oligospermia or azospermia.
申请公布号 WO2015018421(A1) 申请公布日期 2015.02.12
申请号 WO2014DK50235 申请日期 2014.08.04
申请人 RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL 发明人 JENSEN, MARTIN BLOMBERG
分类号 A61K38/00;A61K39/395;A61P15/00;C07K16/28 主分类号 A61K38/00
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