摘要 |
The present invention relates to antagonists or inhibitors, which bind selectively to RANKL/OPGbp and regulate the interaction between RANKL/OPGbp and RANK/OPG.In particular, the present invention relates to an antibody or antigen binding domain, fragment or derivative thereof,immunoreactive with a RANKL/OPGbppeptidefor use in the treatment, prevention or alleviation of male infertility or reduced male fertility such as oligospermia or azospermia. |