PORCINE ASTROVIRUS SEQUENCES AND USES THEREOF

摘要

The invention is directed to isolated porcine astroviruses associated with porcine periweaning failure to thrive syndrome, high morbidity and mortality syndrome in growing pigs, mulberry heart disease, porcine respiratory disease, porcine gastrointestinal disease, or reproductive failure. The invention also relates to isolated nucleic acids sequences and polypeptides derived from porcine astroviruses. Additionally, the invention relates to antibodies against antigens from porcine astroviruses. The invention also relates to iRNAs which target nucleic acid sequences of the porcine astrovirus. The invention is further related to methods for detecting the presence or absence of porcine astroviruses in an animal. The invention is also related to immunogenic compositions for inducing an immune response against porcine astroviruses in an animal.