发明名称 |
AQUEOUS PHARMACEUTICAL COMPOSITION CONTAINING A BIOLOGIC THERAPEUTIC AGENT AND GUANIDINE OR A GUANIDINE DERIVATIVE AND AN INJECTION INCLUDING THE COMPOSITION. |
摘要 |
<p>The present invention is directed to an aqueous pharmaceutical composition, particularly an aqueous ophthalmic composition, suitable as an injection, particularly an intravitreal injection. The composition includes a biologic therapeutic agent (e.g., an isolated monoclonal antibody that specifically binds to a C5 protein) that tends to raise the viscosity of the composition and a guanidine and/or guanidine derivative (e.g., L-arginine) that tends to lower the viscosity of the composition.</p> |
申请公布号 |
MX2014014318(A) |
申请公布日期 |
2015.02.12 |
申请号 |
MX20140014318 |
申请日期 |
2013.05.23 |
申请人 |
NOVARTIS AG |
发明人 |
SCHMITT, DAVID;WALLNY, HANS-JOACHIM |
分类号 |
A61K9/00;A61K47/18;A61K47/26;C07K16/18 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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