发明名称 METHODS FOR TREATING HYPERURICEMIA IN PATIENTS WITH GOUT USING HALOFENATE OR HALOFENIC ACID AND A SECOND URATE-LOWERING AGENT.
摘要 <p>Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a first urate-lowering agent and a second urate-lowering agent. In some aspects the first urate-lowering agent is (-)- halofenate, (-)- halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second urate-lowering agent is an inhibitor of uric acid production, a uricosuric agent, a uricase, or a pharmaceutically acceptable salt thereof.</p>
申请公布号 MX2014005400(A) 申请公布日期 2015.02.12
申请号 MX20140005400 申请日期 2011.11.04
申请人 CYMABAY THERAPEUTICS, INC. 发明人 BRIAN EDWARD LAVAN;GOPAL CHANDRA SAHA;BRIAN K. ROBERTS;CHARLES A. MCWHERTER
分类号 A61K31/19 主分类号 A61K31/19
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