发明名称 |
STABILIZED MODIFIED RELEASE FOLIC ACID DERIVATIVE COMPOSITION, ITS THERAPEUTIC USE AND METHODS OF MANUFACTURE |
摘要 |
This invention relates to an oral stabilized modified release pharmaceutical dosage form containing L-methylfolate calcium, which is primarily absorbed from proximal small intestine via a saturable human proton-coupled folate transporter (h-PCFT) mediated transport intended as monotherapy for the treatment of patients with MDDs and/or diagnosed with dysthymia, schizophrenia, or degenerative dementia of the Alzheimer type. |
申请公布号 |
CA2919213(A1) |
申请公布日期 |
2015.02.05 |
申请号 |
CA20142919213 |
申请日期 |
2014.07.29 |
申请人 |
ADARE PHARMACEUTICALS, INC. |
发明人 |
VENKATESH, GOPI;GUILLOT, MICAEL;LAI, JIN-WANG;GOSSELIN, MICHAEL;BEINBORN, NICOLE |
分类号 |
A61K31/519;A61K9/00;A61K9/22;A61K9/28;A61K47/30 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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