主权项 |
1. A compound according to formula (I), wherein R1 is a group selected from among —H, -halogen, —CN, —O—C1-C4-alkyl, —C1-C4-alkyl, —CH═CH2, —C≡H, —CF3, —OCF3, —OCF2H, —C5-C10-heteroaryl, and —OCFH2, and wherein R7 is a group selected from among —H, -halogen, —CN, —O—C1-C4-alkyl, —C1-C4-alkyl, —CH═CH2, —C≡CH, —CF3, —OCF3, —OCF2H, and —OCFH2; or wherein R7 and R1 on two neighbouring ring atoms together form a —C3-C6-alkenylene group, such that an annellated aromatic ring is formed, in which one or two or three carbon centers may optionally be replaced by 1 or 2 or 3 hetero atoms selected from N, O, and S, wherein the resulting annelated ring being optionally substituted by one or more groups selected from among —OH, —NH2, —C1-C3-alkyl, —O—C1-C6-alkyl, —CN, —CF3, —OCF3, and halogen; wherein R4 is a group selected from among -hydrogen, —C1-C3-alkyl, —CF3, —OCF3, —OCF2H, -halogen, —CN, —O—C1-C4-alkyl, —CH═CH2, —C≡H, and —OCFH2; wherein A is C or N; wherein R14 is a group selected from among -hydrogen, and —C1-C3-alkyl; wherein R2 is selected from among —H, -halogen, —CN, —O—C1-C4-alkyl, —C1-C4-alkyl, -cyclopropyl, —CH═CH2, —C≡H, —CF3, —OCF3, —OCF2H, and —OCFH2; wherein R3 is selected from among —H, -methyl, -ethyl, -propyl, -i-propyl, -cyclopropyl, —OCH3, —CF3, and —CN; wherein n is 1, 2 or 3; wherein G and E are N; wherein R5 is a group of the structure -L1-R13, wherein L1 is selected from among —NH— and —N(C1-C4-alkyl)-, wherein R13 is —C3-C8-heterocyclyl, wherein R13 is optionally substituted by one or more groups selected from among halogen, —CF3, —OCF3, —CN, —OH, —O—C1-C4-alkyl, —C1-C6-alkyl; wherein R6 is selected from among —H, —C1-C4-alkyl, —OH, —O—C1-C4-alkyl, -halogen, —CN, —CF3, and —OCF3; as well as in form of their acid addition salts with pharmacologically acceptable acids. |