Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same

摘要

Compositions and methods effective to minimize or eliminate the presence of oxidative degradation products in solid dosage forms comprising sufentanil are provided.

主权项

1. A packaged solid sufentanil drug dosage form comprising:
(a) a solid sufentanil drug dosage form; (b) a primary package containing said solid sufentanil drug dosage form and an oxygen scavenger, wherein the percentage of sufentanil oxidative degradation products is minimized or eliminated in a solid sufentanil drug dosage form packaged with said oxygen scavenger relative to a solid sufentanil drug dosage form packaged in the absence of an oxygen scavenger.