| 摘要 |
The present invention provides compounds of the formula: (I) in which A is CH2, CHOH, CH2O, CH25, CH2NH, OCH, SCH2, NH, NHCH2, NHCOCH2 or CH2NHCH2, X1 is H, halogen, C1-C4-alkyl or C1-C4-alkoxy, X2 is halogen, C1-C4-alkyl or C1-C4-alkoxy, Z is 2-pyrimidinyl or C(=NR1) NHR2 (where R1 is H and R2 is H, OH or CH2CO2Et, or R1 and R2 together form CH2CH2, CH2CH2CH2 or N=N), and their addition salts. The compounds of formula I and their salts are useful in therapy as hypotensive agents. |
