发明名称 Novel substituted indole derivatives as gamma secretase modulators
摘要 <p>The present disclosure is concerned with novel substituted indole derivatives of Formula (I) wherein R1, R2, R3, A1, A2, A3, Y and X have the meaning defined in the claims. The compounds according to the present disclosure are useful as gamma secretase modulators. The disclosure further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p>
申请公布号 NZ619683(A) 申请公布日期 2015.01.30
申请号 NZ20120619683 申请日期 2012.07.12
申请人 JANSSEN PHARMACEUTICALS INC.;CELLZOME LIMITED 发明人 GIJSEN HENRICUS JACOBUS MARIA;MINNE GARRETT BERLOND;BISCHOFF FRANÇOIS PAUL;VELTER ADRIANA INGRID;PIETERS SERGE MARIA ALOYSIUS;BERTHELOT DIDIER JEAN-CLAUDE
分类号 C07D487/04;A61K31/5383;A61P25/28;C07D498/04 主分类号 C07D487/04
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