发明名称 |
METHOD OF TREATING BENDAMUSTINE-RESPONSIVE CONDITIONS IN PATIENTS REQUIRING REDUCED VOLUMES FOR ADMINISTRATION |
摘要 |
<p>Methods of treating bendamustine responsive conditions in patients having fluid and/or sodium intake restrictions are disclosed. The methods include identifying patients having such restrictions and in need of bendamustine, and then administering thereto a bendamustine-containing composition in a volume of about 100 ml or less intravenously over a period of about 30 minutes or less. The smaller volumes and reduced sodium load as compared to currently known methods of treatment minimize cardiac and/or renal stress in patients having diseases such as congestive heart failure or renal disease.</p> |
申请公布号 |
EP2827863(A1) |
申请公布日期 |
2015.01.28 |
申请号 |
EP20130765020 |
申请日期 |
2013.03.15 |
申请人 |
EAGLE PHARMACEUTICALS, INC. |
发明人 |
SUNDARAM, SRIKANTH;TARRIFF, SCOTT, L. |
分类号 |
A61K31/4184;A61K9/00;A61K47/02;A61K47/10;A61K47/20 |
主分类号 |
A61K31/4184 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|