| 发明名称 |
ENHANCED AFFINITY T CELL RECEPTORS AND METHODS FOR MAKING THE SAME |
| 摘要 |
<p>The present disclosure provides methods for generating enhanced affinity T cell receptors by agonist selection of hematopoietic progenitor cells expressing an antigen specific TCRαcultured with stromal cells expressing Delta-like-1 or Delta-like-4, compositions prepared from such methods, and uses of thereof.</p> |
| 申请公布号 |
KR20150009556(A) |
申请公布日期 |
2015.01.26 |
| 申请号 |
KR20147032747 |
申请日期 |
2013.05.02 |
| 申请人 |
FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
SCHMITT THOMAS M.;GREENBERG PHILIP D. |
| 分类号 |
C07K14/725;A61K35/12;A61P35/00;C07K19/00;C12N5/0783;C12N5/10;C12N15/867 |
主分类号 |
C07K14/725 |
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