发明名称 |
Anticancer fusion protein |
摘要 |
<p>A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a).The fusion protein can be used for the treatment of cancer diseases.</p> |
申请公布号 |
AU2011334868(B2) |
申请公布日期 |
2015.01.22 |
申请号 |
AU20110334868 |
申请日期 |
2011.12.05 |
申请人 |
ADAMED SP. Z O.O. |
发明人 |
PIECZYKOLAN, JERZY SZCZEPAN;LEMKE, KRZYSZTOF KAZIMIERZ;PAWLAK, SEBASTIAN;ZEREK, BARTLOMIEJ |
分类号 |
C07K14/705;A61K38/17;A61K38/21;A61P35/00;C07K14/56;C07K14/57;C12N15/12;C12N15/21;C12N15/23;C12N15/62 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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